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Structure paper

TitleX-ray structure of active site-inhibited clotting factor Xa. Implications for drug design and substrate recognition.
Journal, issue, pagesJ. Biol. Chem., Vol. 271, Page 29988-29992, Year 1996
Publish dateAug 23, 1996 (structure data deposition date)
AuthorsBrandstetter, H. / Kuhne, A. / Bode, W. / Huber, R. / von der Saal, W. / Wirthensohn, K. / Engh, R.A.
External linksJ. Biol. Chem. / PubMed:8939944
MethodsX-ray diffraction
Resolution3 Å
Structure data

PDB-1fax:
COAGULATION FACTOR XA INHIBITOR COMPLEX
Method: X-RAY DIFFRACTION / Resolution: 3 Å

Chemicals

ChemComp-CA:
Unknown entry

ChemComp-DX9:
(2S)-3-(7-carbamimidoylnaphthalen-2-yl)-2-[4-({(3R)-1-[(1Z)-ethanimidoyl]pyrrolidin-3-yl}oxy)phenyl]propanoic acid

Source
  • homo sapiens (human)
KeywordsCOAGULATION FACTOR / GLYCOPROTEIN / HYDROLASE / SERINE PROTEASE / PLASMA / BLOOD COAGULATION FACTOR / GAMMA-CARBOXYGLUTAMIC ACID / CALCIUM-BINDING

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