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Title | High-resolution crystal structures of human cyclin-dependent kinase 2 with and without ATP: bound waters and natural ligand as guides for inhibitor design. |
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Journal, issue, pages | J. Med. Chem., Vol. 39, Page 4540-4546, Year 1996 |
Publish date | Jun 3, 1996 (structure data deposition date) |
![]() | Schulze-Gahmen, U. / De Bondt, H.L. / Kim, S.H. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 1.8 - 1.9 Å |
Structure data | ![]() PDB-1hck: ![]() PDB-1hcl: |
Chemicals | ![]() ChemComp-MG: ![]() ChemComp-ATP: ![]() ChemComp-HOH: |
Source |
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![]() | PROTEIN KINASE / TRANSFERASE / SERINE/THREONINE PROTEIN KINASE / ATP-BINDING / CELL CYCLE / CELL DIVISION / MITOSIS / PHOSPHORYLATION |