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| Title | Structure-based design of HIV protease inhibitors: sulfonamide-containing 5,6-dihydro-4-hydroxy-2-pyrones as non-peptidic inhibitors. |
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| Journal, issue, pages | J. Med. Chem., Vol. 39, Page 4349-4353, Year 1996 |
| Publish date | Oct 5, 1999 (structure data deposition date) |
 Authors | Thaisrivongs, S. / Skulnick, H.I. / Turner, S.R. / Strohbach, J.W. / Tommasi, R.A. / Johnson, P.D. / Aristoff, P.A. / Judge, T.M. / Gammill, R.B. / Morris, J.K. ...Thaisrivongs, S. / Skulnick, H.I. / Turner, S.R. / Strohbach, J.W. / Tommasi, R.A. / Johnson, P.D. / Aristoff, P.A. / Judge, T.M. / Gammill, R.B. / Morris, J.K. / Romines, K.R. / Chrusciel, R.A. / Hinshaw, R.R. / Chong, K.T. / Tarpley, W.G. / Poppe, S.M. / Slade, D.E. / Lynn, J.C. / Horng, M.M. / Tomich, P.K. / Seest, E.P. / Dolak, L.A. / Howe, W.J. / Howard, G.M. / Watenpaugh, K.D. |
 External links | J. Med. Chem. / PubMed:8893827 |
| Methods | X-ray diffraction |
| Resolution | 1.97 - 2.5 Å |
| Structure data |  PDB-1d4s:  PDB-1d4y: |
| Chemicals |  ChemComp-TPV:  ChemComp-HOH: |
| Source |
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 Keywords | HYDROLASE / ACID PROTEASE / ASPARTYL PROTEASE |
human immunodeficiency virus 1