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TitleSynthesis, structure, and structure-activity relationships of divalent thrombin inhibitors containing an alpha-keto-amide transition-state mimetic.
Journal, issue, pagesProtein Sci., Vol. 5, Page 422-433, Year 1996
Publish dateJul 20, 1995 (structure data deposition date)
AuthorsKrishnan, R. / Tulinsky, A. / Vlasuk, G.P. / Pearson, D. / Vallar, P. / Bergum, P. / Brunck, T.K. / Ripka, W.C.
External linksPubMed:8868478
MethodsX-ray diffraction
Resolution2.3 Å
Structure data

PDB-1dit:
COMPLEX OF A DIVALENT INHIBITOR WITH THROMBIN
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE/HYDROLASE INHIBITOR / HYDROLASE / BLOOD COAGULATION / INHIBITOR / HYDROLASE-HYDROLASE INHIBITOR COMPLEX

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