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TitleStructure and inhibition of plasmepsin II, a hemoglobin-degrading enzyme from Plasmodium falciparum.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 93, Page 10034-10039, Year 1996
Publish dateJun 11, 1996 (structure data deposition date)
AuthorsSilva, A.M. / Lee, A.Y. / Gulnik, S.V. / Maier, P. / Collins, J. / Bhat, T.N. / Collins, P.J. / Cachau, R.E. / Luker, K.E. / Gluzman, I.Y. ...Silva, A.M. / Lee, A.Y. / Gulnik, S.V. / Maier, P. / Collins, J. / Bhat, T.N. / Collins, P.J. / Cachau, R.E. / Luker, K.E. / Gluzman, I.Y. / Francis, S.E. / Oksman, A. / Goldberg, D.E. / Erickson, J.W.
External linksProc. Natl. Acad. Sci. USA / PubMed:8816746
MethodsX-ray diffraction
Resolution2.7 Å
Structure data

PDB-1sme:
PLASMEPSIN II, A HEMOGLOBIN-DEGRADING ENZYME FROM PLASMODIUM FALCIPARUM, IN COMPLEX WITH PEPSTATIN A
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • plasmodium falciparum (malaria parasite P. falciparum)
  • streptomyces argenteolus subsp. toyonakensis (bacteria)
KeywordsHYDROLASE/HYDROLASE INHIBITOR / ASPARTYL PROTEINASE / ASPARTIC PROTEINASE / ASPARTYL PROTEASE / HYDROLASE-HYDROLASE INHIBITOR complex

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