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TitleFunctional mimicry of a protein hormone by a peptide agonist: the EPO receptor complex at 2.8 A.
Journal, issue, pagesScience, Vol. 273, Page 464-471, Year 1996
Publish dateMay 7, 1996 (structure data deposition date)
AuthorsLivnah, O. / Stura, E.A. / Johnson, D.L. / Middleton, S.A. / Mulcahy, L.S. / Wrighton, N.C. / Dower, W.J. / Jolliffe, L.K. / Wilson, I.A.
External linksPubMed:8662530
MethodsX-ray diffraction
Resolution2.8 Å
Structure data

PDB-1ebp:
COMPLEX BETWEEN THE EXTRACELLULAR DOMAIN OF ERYTHROPOIETIN (EPO) RECEPTOR [EBP] AND AN AGONIST PEPTIDE [EMP1]
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Source
  • homo sapiens (human)
KeywordsCOMPLEX (CYTOKINE RECEPTOR/PEPTIDE) / ERYTHROPOIETIN RECEPTOR / SIGNAL TRANSDUCTION / PROTEIN MINIMIZATION / DRUG DESIGN / CYTOKINE RECEPTOR CLASS 1 / COMPLEX (CYTOKINE RECEPTOR-PEPTIDE) / COMPLEX (CYTOKINE RECEPTOR-PEPTIDE) complex

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