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TitleCrystal structures of the recombinant kringle 1 domain of human plasminogen in complexes with the ligands epsilon-aminocaproic acid and trans-4-(aminomethyl)cyclohexane-1-carboxylic Acid.
Journal, issue, pagesBiochemistry, Vol. 35, Page 2567-2576, Year 1996
Publish dateDec 3, 1995 (structure data deposition date)
AuthorsMathews, I.I. / Vanderhoff-Hanaver, P. / Castellino, F.J. / Tulinsky, A.
External linksBiochemistry / PubMed:8611560
MethodsX-ray diffraction
Resolution2.06 - 2.07 Å
Structure data

PDB-1cea:
THE STRUCTURE OF THE NON-COVALENT COMPLEX OF RECOMBINANT KRINGLE 1 DOMAIN OF HUMAN PLASMINOGEN WITH EACA (EPSILON-AMINOCAPROIC ACID)
Method: X-RAY DIFFRACTION / Resolution: 2.06 Å

PDB-1ceb:
THE STRUCTURE OF THE NON-COVALENT COMPLEX OF RECOMBINANT KRINGLE 1 DOMAIN OF HUMAN PLASMINOGEN WITH AMCHA (TRANS-4-AMINOMETHYLCYCLOHEXANE-1-CARBOXYLIC ACID)
Method: X-RAY DIFFRACTION / Resolution: 2.07 Å

Chemicals

ChemComp-ACA:
6-AMINOHEXANOIC ACID / inhibitor*YM

ChemComp-HOH:
WATER

ChemComp-AMH:
TRANS-4-AMINOMETHYLCYCLOHEXANE-1-CARBOXYLIC ACID / medication*YM

Source
  • homo sapiens (human)
KeywordsSERINE PROTEASE

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