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Structure paper

TitleThe crystal structure of the complex of blood coagulation factor VIIa with soluble tissue factor.
Journal, issue, pagesNature, Vol. 380, Page 41-46, Year 1996
Publish dateMar 5, 1997 (structure data deposition date)
AuthorsBanner, D.W. / D'Arcy, A. / Chene, C. / Winkler, F.K. / Guha, A. / Konigsberg, W.H. / Nemerson, Y. / Kirchhofer, D.
External linksNature / PubMed:8598903
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-1dan:
Complex of active site inhibited human blood coagulation factor VIIA with human recombinant soluble tissue factor
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-BGC:
beta-D-glucopyranose

ChemComp-FUC:
alpha-L-fucopyranose

ChemComp-CA:
Unknown entry

ChemComp-0Z6:
D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-phenylalaninamide

ChemComp-CAC:
CACODYLATE ION

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE/HYDROLASE INHIBITOR / BLOOD COAGULATION / SERINE PROTEASE / CO-FACTOR / RECEPTOR ENZYME / GLA / EGF / HYDROLASE-HYDROLASE INHIBITOR COMPLEX

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