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TitleStructural analysis of human alpha-class glutathione transferase A1-1 in the apo-form and in complexes with ethacrynic acid and its glutathione conjugate.
Journal, issue, pagesStructure, Vol. 3, Page 717-727, Year 1995
Publish dateJun 9, 1995 (structure data deposition date)
AuthorsCameron, A.D. / Sinning, I. / L'Hermite, G. / Olin, B. / Board, P.G. / Mannervik, B. / Jones, T.A.
External linksStructure / PubMed:8591048
MethodsX-ray diffraction
Resolution2 - 2.7 Å
Structure data

PDB-1gsd:
GLUTATHIONE TRANSFERASE A1-1 IN UNLIGANDED FORM
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-1gse:
GLUTATHIONE TRANSFERASE A1-1 COMPLEXED WITH AN ETHACRYNIC ACID GLUTATHIONE CONJUGATE (MUTANT R15K)
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-1gsf:
GLUTATHIONE TRANSFERASE A1-1 COMPLEXED WITH ETHACRYNIC ACID
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-GSH:
GLUTATHIONE

ChemComp-EAA:
ETHACRYNIC ACID

ChemComp-BME:
BETA-MERCAPTOETHANOL

Source
  • homo sapiens (human)
KeywordsTRANSFERASE (GLUTATHIONE) / A1-1

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