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Structure paper

TitleRefined 1.8 A structure of human aldose reductase complexed with the potent inhibitor zopolrestat.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 90, Page 9847-9851, Year 1993
Publish dateJul 20, 1993 (structure data deposition date)
AuthorsWilson, D.K. / Tarle, I. / Petrash, J.M. / Quiocho, F.A.
External linksProc. Natl. Acad. Sci. USA / PubMed:8234324
MethodsX-ray diffraction
Resolution1.8 Å
Structure data

PDB-1mar:
REFINED 1.8 ANGSTROMS STRUCTURE OF HUMAN ALDOSE REDUCTASE COMPLEXED WITH THE POTENT INHIBITOR ZOPOLRESTAT
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-NAP:
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE

ChemComp-ZST:
3,4-DIHYDRO-4-OXO-3-((5-TRIFLUOROMETHYL-2-BENZOTHIAZOLYL)METHYL)-1-PHTHALAZINE ACETIC ACID

Source
  • homo sapiens (human)
KeywordsOXIDOREDUCTASE(NADP)

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