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TitleThe X-Ray Structure of (Mebm2T)1-Cyclosporin Complexed with Cyclophilin a Provides an Explanation for its Anomalously High Immunosuppressive Activity.
Journal, issue, pagesProtein Eng., Vol. 7, Page 597-, Year 1994
Publish dateSep 6, 1995 (structure data deposition date)
AuthorsMikol, V. / Kallen, J. / Walkinshaw, M.D.
External linksProtein Eng. / PubMed:8073029
MethodsX-ray diffraction
Resolution2.2 Å
Structure data

PDB-1cwb:
THE X-RAY STRUCTURE OF (MEBM2T)1-CYCLOSPORIN COMPLEXED WITH CYCLOPHILIN A PROVIDES AN EXPLANATION FOR ITS ANOMALOUSLY HIGH IMMUNOSUPPRESSIVE ACTIVITY
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • tolypocladium inflatum (fungus)
KeywordsISOMERASE/IMMUNOSUPPRESSANT / ISOMERASE-IMMUNOSUPPRESSANT COMPLEX / CYCLOPHILIN-CYCLOSPORIN COMPLEX / CYCLOSPORIN A / IMMUNOSUPPRESSANT / CYCLOPHILIN

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