+Search query
-Structure paper
Title | Methotrexate-resistant variants of human dihydrofolate reductase with substitutions of leucine 22. Kinetics, crystallography, and potential as selectable markers. |
---|---|
Journal, issue, pages | J. Biol. Chem., Vol. 270, Page 5057-5064, Year 1995 |
Publish date | Jan 25, 1995 (structure data deposition date) |
![]() | Lewis, W.S. / Cody, V. / Galitsky, N. / Luft, J.R. / Pangborn, W. / Chunduru, S.K. / Spencer, H.T. / Appleman, J.R. / Blakley, R.L. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 2.3 Å |
Structure data | ![]() PDB-1dlr: ![]() PDB-1dls: |
Chemicals | ![]() ChemComp-NDP: ![]() ChemComp-MXA: ![]() ChemComp-HOH: ![]() ChemComp-MTX: |
Source |
|
![]() | OXIDOREDUCTASE / OXIDO-REDUCTASE |