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TitleMutation of a buried residue causes loss of activity but no conformational change in the heat-labile enterotoxin of Escherichia coli.
Journal, issue, pagesNat. Struct. Biol., Vol. 2, Page 269-272, Year 1995
Publish dateFeb 15, 1995 (structure data deposition date)
AuthorsMerritt, E.A. / Sarfaty, S. / Pizza, M. / Domenighini, M. / Rappuoli, R. / Hol, W.G.
External linksNat. Struct. Biol. / PubMed:7796260
MethodsX-ray diffraction
Resolution2.5 Å
Structure data

PDB-1htl:
MUTATION OF A BURIED RESIDUE CAUSES LACK OF ACTIVITY BUT NO CONFORMATIONAL CHANGE: CRYSTAL STRUCTURE OF E. COLI HEAT-LABILE ENTEROTOXIN MUTANT VAL 97--> LYS
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • escherichia coli (E. coli)
KeywordsENTEROTOXIN

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