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TitleImproved calcineurin inhibition by yeast FKBP12-drug complexes. Crystallographic and functional analysis.
Journal, issue, pagesJ. Biol. Chem., Vol. 268, Page 7607-7609, Year 1993
Publish dateJan 6, 1993 (structure data deposition date)
AuthorsRotonda, J. / Burbaum, J.J. / Chan, H.K. / Marcy, A.I. / Becker, J.W.
External linksPubMed:7681823
MethodsX-ray diffraction
Resolution2.5 Å
Structure data

PDB-1yat:
IMPROVED CALCINEURIN INHIBITION BY YEAST FKBP12-DRUG COMPLEXES. CRYSTALLOGRAPHIC AND FUNCTIONAL ANALYSIS
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-FK5:
8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN / medication*YM

ChemComp-HOH:
WATER

Source
  • saccharomyces cerevisiae (brewer's yeast)
KeywordsBINDING PROTEIN

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