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Structure paper

TitleHigh resolution crystal structures of recombinant human renin in complex with polyhydroxymonoamide inhibitors.
Journal, issue, pagesJ. Mol. Biol., Vol. 250, Page 211-222, Year 1995
Publish dateMar 31, 1995 (structure data deposition date)
AuthorsTong, L. / Pav, S. / Lamarre, D. / Pilote, L. / LaPlante, S. / Anderson, P.C. / Jung, G.
External linksJ. Mol. Biol. / PubMed:7608971
MethodsX-ray diffraction
Resolution1.8 Å
Structure data

PDB-1hrn:
HIGH RESOLUTION CRYSTAL STRUCTURES OF RECOMBINANT HUMAN RENIN IN COMPLEX WITH POLYHYDROXYMONOAMIDE INHIBITORS
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-03D:
(2R,4S,5S)-N-[(2S,3R,4S)-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]-2-(cyclopropylmethyl)-4,5-dihydroxy-6-phenylhexanamide

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE/HYDROLASE INHIBITOR / ASPARTIC PROTEINASE / HYDROLASE-HYDROLASE INHIBITOR complex

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