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Structure paper

TitleThree-dimensional crystal structure of the A-tract DNA dodecamer d(CGCAAATTTGCG) complexed with the minor-groove-binding drug Hoechst 33258.
Journal, issue, pagesEur. J. Biochem., Vol. 222, Page 721-726, Year 1994
Publish dateSep 22, 1994 (structure data deposition date)
AuthorsVega, M.C. / Garcia Saez, I. / Aymami, J. / Eritja, R. / Van der Marel, G.A. / Van Boom, J.H. / Rich, A. / Coll, M.
External linksEur. J. Biochem. / PubMed:7517864
MethodsX-ray diffraction
Resolution2.44 Å
Structure data

PDB-264d:
THREE-DIMENSIONAL CRYSTAL STRUCTURE OF THE A-TRACT DNA DODECAMER D(CGCAAATTTGCG) COMPLEXED WITH THE MINOR-GROOVE-BINDING DRUG HOECHST 33258
Method: X-RAY DIFFRACTION / Resolution: 2.44 Å

Chemicals

ChemComp-HT:
2'-(4-HYDROXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE

ChemComp-HOH:
WATER

KeywordsDNA / B-DNA / DOUBLE HELIX / COMPLEXED WITH DRUG

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