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Structure paper

TitleSequence-dependent effects in drug-DNA interaction: the crystal structure of Hoechst 33258 bound to the d(CGCAAATTTGCG)2 duplex.
Journal, issue, pagesNucleic Acids Res., Vol. 22, Page 1607-1612, Year 1994
Publish dateJul 21, 1994 (structure data deposition date)
AuthorsSpink, N. / Brown, D.G. / Skelly, J.V. / Neidle, S.
External linksNucleic Acids Res. / PubMed:7515488
MethodsX-ray diffraction
Resolution2.25 Å
Structure data

PDB-296d:
SEQUENCE-DEPENDENT EFFECTS IN DRUG-DNA INTERACTION: THE CRYSTAL STRUCTURE OF HOECHST 33258 BOUND TO THE D(CGCAAATTTGCG)2 DUPLEX
Method: X-RAY DIFFRACTION / Resolution: 2.25 Å

Chemicals

ChemComp-HT:
2'-(4-HYDROXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE

ChemComp-HOH:
WATER

KeywordsDNA / B-DNA / DOUBLE HELIX / COMPLEXED WITH DRUG

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