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TitleStructural studies on human rhinovirus 14 drug-resistant compensation mutants.
Journal, issue, pagesJ. Mol. Biol., Vol. 253, Page 61-73, Year 1995
Publish dateJun 9, 1995 (structure data deposition date)
AuthorsHadfield, A.T. / Oliveira, M.A. / Kim, K.H. / Minor, I. / Kremer, M.J. / Heinz, B.A. / Shepard, D. / Pevear, D.C. / Rueckert, R.R. / Rossmann, M.G.
External linksJ. Mol. Biol. / PubMed:7473717
MethodsX-ray diffraction
Resolution2.9 - 3.1 Å
Structure data

PDB-1ruc:
RHINOVIRUS 14 MUTANT N1105S COMPLEXED WITH ANTIVIRAL COMPOUND WIN 52035
Method: X-RAY DIFFRACTION / Resolution: 3.1 Å

PDB-1rud:
RHINOVIRUS 14 MUTANT N1105S COMPLEXED WITH ANTIVIRAL COMPOUND WIN 52084
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

PDB-1rue:
RHINOVIRUS 14 SITE DIRECTED MUTANT N1219A COMPLEXED WITH ANTIVIRAL COMPOUND WIN 52035
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

PDB-1ruf:
RHINOVIRUS 14 (HRV14) (MUTANT WITH ASN 1 219 REPLACED BY ALA (N219A IN CHAIN 1)
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

PDB-1rug:
RHINOVIRUS 14 MUTANT N1219S COMPLEXED WITH ANTIVIRAL COMPOUND WIN 52035
Method: X-RAY DIFFRACTION / Resolution: 3 Å

PDB-1ruh:
RHINOVIRUS 14 MUTANT N1219S COMPLEXED WITH ANTIVIRAL COMPOUND WIN 52084
Method: X-RAY DIFFRACTION / Resolution: 3 Å

PDB-1rui:
RHINOVIRUS 14 MUTANT S1223G COMPLEXED WITH ANTIVIRAL COMPOUND WIN 52084
Method: X-RAY DIFFRACTION / Resolution: 3 Å

PDB-1ruj:
RHINOVIRUS 14 MUTANT WITH SER 1 223 REPLACED BY GLY (S1223G)
Method: X-RAY DIFFRACTION / Resolution: 3 Å

Chemicals

ChemComp-W35:
5-(5-(4-(4,5-DIHYDRO-2-OXAZOLY)PHENOXY)PENTYL)-3-METHYL ISOXAZOLE

ChemComp-W84:
5-(7-(5-HYDRO-4-METHYL-2-OXAZOLYL)PHENOXY)HEPTYL)-3-METHYL ISOXAZOLE

Source
  • human rhinovirus 14
KeywordsVIRUS / RHINOVIRUS COAT PROTEIN / Icosahedral virus

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