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TitleTuning Au Reactivity Beyond Canonical Targets: Ligand-Driven Au(I) Metalation of Lysine Residues in Hen Egg White Lysozyme.
Journal, issue, pagesInorg. Chem., Vol. 65, Page 16296-16304, Year 2026
Publish dateMar 26, 2026 (structure data deposition date)
AuthorsPiroddu, D. / Famlonga, L. / Tolbatov, I. / Ferraro, G. / Chiaverini, L. / Merlino, A. / La Mendola, D. / Marrone, A. / Marzo, T.
External linksInorg. Chem. / PubMed:42417613
MethodsX-ray diffraction
Resolution1.441 - 1.54 Å
Structure data

PDB-29oh:
X-ray structure of the adduct formed upon reaction of the gold compound AF-Npx with lysozyme (Structure 1)
Method: X-RAY DIFFRACTION / Resolution: 1.54 Å

PDB-29ol:
X-ray structure of the adduct formed upon reaction of the gold compound AF-Npx with lysozyme (Structure 2)
Method: X-RAY DIFFRACTION / Resolution: 1.441 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-AU:
Unknown entry

ChemComp-HOH:
WATER

Source
  • gallus gallus (chicken)
KeywordsHYDROLASE / gold / auranofin / naproxene / lysozyme / gold-protein interaction / lysine

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