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Structure paper

TitleISGylation mechanism uncovers conformational specificity for HECT-family E3 ligase HERC5.
Journal, issue, pagesCell Rep, Vol. 45, Page 117565-117565, Year 2026
Publish dateFeb 13, 2025 (structure data deposition date)
AuthorsSahoo, P. / Parmar, G.G. / Lenka, D.R. / Sherawat, M. / Trivedi, B.S. / Kumar, A.
External linksCell Rep / PubMed:42322607
MethodsX-ray diffraction
Resolution2.7 Å
Structure data

PDB-9lw4:
UbCh8-ISG15 complex
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

Chemicals

ChemComp-CL:
Unknown entry

ChemComp-3CN:
3-AMINOPROPANE

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / ISG15 conjugation.

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