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TitleCrystal structure of the CD33/Fab-10C8 complex elucidates the mechanism of antibody antagonism in HBV-induced immunosuppression.
Journal, issue, pagesJ. Biomed. Sci., Vol. 33, Year 2026
Publish dateJun 24, 2025 (structure data deposition date)
AuthorsYeh, Y.H. / Lin, M.G. / Sung, P.S. / Hsieh, S.L. / Hsiao, C.D.
External linksJ. Biomed. Sci. / PubMed:42215976
MethodsX-ray diffraction
Resolution3.18 Å
Structure data

PDB-9vl2:
Structure of CD33 complexed with its mAb-10C8
Method: X-RAY DIFFRACTION / Resolution: 3.18 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / CD33 Siglec-3 HBV infection immune checkpoint

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