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TitleAAK1-mediated phosphorylation of PDLIM5 and Talin1 promotes focal adhesion disassembly to accelerate cell migration.
Journal, issue, pagesNat Commun, Year 2026
Publish dateMay 2, 2024 (structure data deposition date)
AuthorsKrocianova, D. / Dagg, A.D. / Clayton, R.A. / Potesil, D. / Fedorova, V. / Harmanec, A. / Benova, V. / Bosakova, V. / Kaufman, J.G.G. / Martinkova, P. ...Krocianova, D. / Dagg, A.D. / Clayton, R.A. / Potesil, D. / Fedorova, V. / Harmanec, A. / Benova, V. / Bosakova, V. / Kaufman, J.G.G. / Martinkova, P. / Alblova, M. / Kelly, B.T. / Hanakova, K. / Roudnicky, P. / Spielman, S.J. / Fric, J. / Sroubek, F. / Houser, J. / Wrobel, A.G. / Boura, E. / Owen, D.J. / Zdrahal, Z. / Kadlecova, Z.
External linksNat Commun / PubMed:42082516
MethodsX-ray diffraction
Resolution1 Å
Structure data

PDB-9f6s:
PDZ domain in complex with the peptide from AP2-associated protein kinase 1
Method: X-RAY DIFFRACTION / Resolution: 1 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsCYTOSOLIC PROTEIN / PDZ; AP2; kinase;

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