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TitleAGAP1 and noncanonical GDP binding regulate triple-negative breast cancer development.
Journal, issue, pagesCell. Mol. Life Sci., Vol. 83, Year 2026
Publish dateMay 10, 2025 (structure data deposition date)
AuthorsZhang, Y. / Zhang, S. / Deng, X. / Cheng, N. / Wang, J. / Huang, H. / Zhuo, Z. / Ye, S. / Yu, X. / Li, Z. ...Zhang, Y. / Zhang, S. / Deng, X. / Cheng, N. / Wang, J. / Huang, H. / Zhuo, Z. / Ye, S. / Yu, X. / Li, Z. / Meng, G. / Zhang, H.
External linksCell. Mol. Life Sci. / PubMed:42002626
MethodsX-ray diffraction
Resolution2.49 Å
Structure data

PDB-9uvl:
Crystal structure of AGAP1-GDP complex
Method: X-RAY DIFFRACTION / Resolution: 2.49 Å

Chemicals

ChemComp-GDP:
GUANOSINE-5'-DIPHOSPHATE / GDP, energy-carrying molecule*YM

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsCELL INVASION / Triple-negative breast cancer; AGAP1; noncanonical GDP binding; carcinogenesis / structure biology

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