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TitleStructural and genetic analysis of neutralizing antibodies reveals mechanisms of GII.4 norovirus antigenic evolution.
Journal, issue, pagesRes Sq, Year 2026
Publish dateFeb 23, 2026 (structure data deposition date)
AuthorsParra, G. / Pilewski, K. / Ghosh, A. / Tohma, K. / Ford-Siltz, L. / Hernandez, A. / Pajuelo, M. / Landivar, M. / DuBois, R.
External linksRes Sq / PubMed:41960338
MethodsX-ray diffraction
Resolution2.7 - 3.36 Å
Structure data

PDB-11ha:
Crystal structure of a GII.4 norovirus capsid P domain in complex with neutralizing antibody 24C10
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

PDB-11hb:
Crystal structure of a GII.4 norovirus capsid P domain in complex with neutralizing antibody 17A5
Method: X-RAY DIFFRACTION / Resolution: 3.36 Å

Source
  • norovirus gii.4 sydney 2012
  • mus musculus (house mouse)
KeywordsVIRAL PROTEIN / Norovirus GII.4 / P domain / Capsid protein / Antibody

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