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TitleTargeting Helicobacter pylori thymidylate kinase: structural insights and validation of novel inhibitors.
Journal, issue, pagesJ. Struct. Biol., Vol. 218, Page 108319-108319, Year 2026
Publish dateAug 18, 2025 (structure data deposition date)
AuthorsKumari, K. / Khan, F.M. / Bose, M. / Ls, R.J. / Yadav, A. / Mondal, N. / Gourinath, S.
External linksJ. Struct. Biol. / PubMed:41935652
MethodsX-ray diffraction
Resolution2.5 Å
Structure data

PDB-9wd2:
Thymidylate kinase of Helicobacter pylori
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-TMP:
THYMIDINE-5'-PHOSPHATE

ChemComp-ANP:
PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER / AMP-PNP, energy-carrying molecule analogue*YM

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

Source
  • helicobacter pylori 26695 (bacteria)
KeywordsCYTOSOLIC PROTEIN / kinase / dTMP / dTDP / thymidine synthesis

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