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Structure paper

TitleMonoclonal antibodies from COVID-19 convalescent patients target cryptic epitopes for broad SARS-CoV-2 neutralization.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 123, Page e2523864123-e2523864123, Year 2026
Publish dateAug 7, 2025 (structure data deposition date)
AuthorsHarit, A. / Mor, M. / Yefet, R. / Izhaki-Tavor, L.S. / Gal-Tanamy, M. / Freund, N.T. / Dessau, M.
External linksProc. Natl. Acad. Sci. USA / PubMed:41880581
MethodsX-ray diffraction
Resolution2.12 - 2.56 Å
Structure data

PDB-9sat:
Monoclonal Antibodies from COVID-19 Convalescent Patients Target Cryptic Epitopes for Universal SARS-CoV-2 Neutralization
Method: X-RAY DIFFRACTION / Resolution: 2.56 Å

PDB-9sbb:
Monoclonal Antibodies from COVID-19 Convalescent Patients Target Cryptic Epitopes for Universal SARS-CoV-2 Neutralization
Method: X-RAY DIFFRACTION / Resolution: 2.12 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-GOL:
GLYCEROL

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-LI:
Unknown entry

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

Source
  • homo sapiens (human)
  • severe acute respiratory syndrome coronavirus 2
KeywordsVIRAL PROTEIN / Immune complex / SARS-CoV-2 / receptor binding domain / neutralizing antibody

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