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Structure paper

TitleSite-specific ribozyme-mediated alkylation of DNA substrates.
Journal, issue, pagesNucleic Acids Res., Vol. 54, Year 2026
Publish dateOct 31, 2024 (structure data deposition date)
AuthorsHe, Y. / Wilson, T.J. / Deng, J. / Luo, Y. / Yan, K. / Xie, Y. / Lilley, D.M.J. / Huang, L.
External linksNucleic Acids Res. / PubMed:41854073
MethodsX-ray diffraction
Resolution2.65 - 2.82 Å
Structure data

PDB-9kbr:
Crystal structure of the methyltransferase-ribozyme 1 bound to DNA substrate (with 1-methyl-adenosine)
Method: X-RAY DIFFRACTION / Resolution: 2.65 Å

PDB-9kfv:
Crystal structure of the methyltransferase-ribozyme 1 bound to DNA substrate (1-benzyl-adenosine derivative)
Method: X-RAY DIFFRACTION / Resolution: 2.82 Å

Chemicals

ChemComp-NA:
Unknown entry

ChemComp-GUN:
GUANINE

ChemComp-HOH:
WATER

ChemComp-K:
Unknown entry

Source
  • synthetic construct (others)
KeywordsDNA-RNA HYBRID / Ribozyme / Methyltransferase / MTR1 / O6-methylguanine / O6-benzylguanine

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