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Structure paper

TitlePyridoxal 5'-Phosphate-Dependent Enzymatic Decarboxylative Annulation.
Journal, issue, pagesJ. Am. Chem. Soc., Vol. 148, Page 9709-9719, Year 2026
Publish dateSep 25, 2024 (structure data deposition date)
AuthorsChai, W. / Luo, S. / Xi, W. / He, X. / Zhang, T. / Zou, Y. / Hai, Y.
External linksJ. Am. Chem. Soc. / PubMed:41769737
MethodsX-ray diffraction
Resolution1.85 - 1.92 Å
Structure data

PDB-9dri:
Crystal structure of SphA in complex with VGQ intermedaite
Method: X-RAY DIFFRACTION / Resolution: 1.85 Å

PDB-9pep:
Crystal structure of holo-pvspha
Method: X-RAY DIFFRACTION / Resolution: 1.92 Å

Chemicals

ChemComp-TRS:
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL / pH buffer*YM

PDB-1bc7:
SERUM RESPONSE FACTOR ACCESSORY PROTEIN 1A (SAP-1)/DNA COMPLEX

ChemComp-HOH:
WATER

Source
  • aspergillus fumigatus (mold)
  • paecilomyces variotii (fungus)
KeywordsBIOSYNTHETIC PROTEIN / PLP-dependent enzyme / synthase

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