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TitleCrystal structures of two different 4-aminobutyrate aminotransferase-like racemases from the hyperthermophilic archaeon Pyrococcus horikoshii.
Journal, issue, pagesInt. J. Biol. Macromol., Vol. 352, Page 151119-151119, Year 2026
Publish dateSep 11, 2025 (structure data deposition date)
AuthorsKawakami, R. / Nishimoto, Y. / Kawase, T. / Hayashi, J. / Yoneda, K. / Ohshima, T. / Sakuraba, H.
External linksInt. J. Biol. Macromol. / PubMed:41759851
MethodsX-ray diffraction
Resolution2.1 - 2.87 Å
Structure data

PDB-9wqz:
Ala/Ser-specific racemase in complex with PLP-D-Ala
Method: X-RAY DIFFRACTION / Resolution: 2.16 Å

PDB-9wr1:
Ala/Ser-specific racemase in complex with PLP-L-Ala
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-9wrf:
Amino acid racemase in complex with PLP-L-Ile
Method: X-RAY DIFFRACTION / Resolution: 2.87 Å

PDB-9wrg:
Amino acid racemase in complex with PLP-D-allo-Ile
Method: X-RAY DIFFRACTION / Resolution: 2.68 Å

PDB-9wu1:
Amino acid racemase in complex with PLP-D-Phe
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-PDD:
N-(5'-PHOSPHOPYRIDOXYL)-D-ALANINE

ChemComp-HOH:
WATER

ChemComp-PP3:
ALANYL-PYRIDOXAL-5'-PHOSPHATE

ChemComp-7VO:
(2S,3S)-3-methyl-2-[[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylamino]pentanoic acid

ChemComp-ILP:
N-[O-PHOSPHONO-PYRIDOXYL]-ISOLEUCINE

PDB-1mb8:
Crystal Structure of the actin binding domain of plectin

Source
  • pyrococcus horikoshii (archaea)
KeywordsISOMERASE / fold type 1 / racemase

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