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Structure paper

TitleRu and Rh binding sites in the structure of human serum transferrin with Fe 3+ bound at the C-lobe.
Journal, issue, pagesDalton Trans, Vol. 55, Page 4051-4056, Year 2026
Publish dateFeb 8, 2026 (structure data deposition date)
AuthorsBanneville, A.S. / Ferraro, G. / D'Elia, R. / Cornaciu-Hoffmann, I. / Pica, A. / Merlino, A.
External linksDalton Trans / PubMed:41738634
MethodsX-ray diffraction
Resolution2.262 - 2.37 Å
Structure data

PDB-28mr:
X-ray structure of the adduct between human serum transferrin with Fe3+ bound at the C-lobe and diruthenium tetraacetate chloride
Method: X-RAY DIFFRACTION / Resolution: 2.262 Å

PDB-28ms:
X-ray structure of the adduct between human serum transferrin with Fe3+ bound at the C-lobe and dirhodium tetraacetate
Method: X-RAY DIFFRACTION / Resolution: 2.37 Å

Chemicals

ChemComp-FE:
Unknown entry

ChemComp-MLI:
MALONATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-ACT:
ACETATE ION

ChemComp-RU:
RUTHENIUM ION

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

PDB-1jz3:
E. COLI (lacZ) BETA-GALACTOSIDASE-TRAPPED 2-DEOXY-GALACTOSYL ENZYME INTERMEDIATE

Source
  • homo sapiens (human)
KeywordsMETAL TRANSPORT / human transferrin / diruthenium / iron / drug delivery / protein-metal interaction

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