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TitleThe CspC:CspA heterodimer transduces germinant and co-germinant signals during Clostridioides difficile spore germination.
Journal, issue, pagesPlos Biol., Vol. 24, Page e3003610-e3003610, Year 2026
Publish dateJul 23, 2025 (structure data deposition date)
AuthorsMcNellis, M.E. / Gonzalez-Del Pino, G. / Serrano-Jimenez, J.A. / Forster, E.R. / Stoica, A.I. / Heldwein, E.E. / Shen, A.
External linksPlos Biol. / PubMed:41628221
MethodsX-ray diffraction
Resolution3.26 - 3.35 Å
Structure data

PDB-9pr8:
Crystal Structure of the Clostridiodes difficile CspC-CspA heterodimer.
Method: X-RAY DIFFRACTION / Resolution: 3.35 Å

PDB-9pr9:
Crystal structure of the Clostridiodes difficile CspA homodimer
Method: X-RAY DIFFRACTION / Resolution: 3.26 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • clostridia (bacteria)
KeywordsSIGNALING PROTEIN / Pseudoproteases / heterodimer / signaling proteins / homodimer

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