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TitleComplex-specific inhibitors for interrogating ATAC histone acetyltransferase complex.
Journal, issue, pagesNat. Chem. Biol., Vol. 22, Page 471-481, Year 2026
Publish dateJul 14, 2025 (structure data deposition date)
AuthorsLiu, S. / Liu, J. / Wu, Y. / Yao, X. / Li, X. / Dong, X. / Li, Q. / Cheung, H.J.H. / Wong, K.Y. / Li, Y. ...Liu, S. / Liu, J. / Wu, Y. / Yao, X. / Li, X. / Dong, X. / Li, Q. / Cheung, H.J.H. / Wong, K.Y. / Li, Y. / He, M. / Chiang, C.L. / Wong, J.W.H. / Li, H. / Wang, W. / Li, X.D.
External linksNat. Chem. Biol. / PubMed:41513852
MethodsX-ray diffraction
Resolution2.88 Å
Structure data

PDB-9pku:
Crystal Structure of YEATS domain of human YEATS2 in complex with LS-131 peptide
Method: X-RAY DIFFRACTION / Resolution: 2.88 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-BZ2:
1-benzofuran-2-carboxylic acid

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsGENE REGULATION / ATAC complex / YEATS2 / chemical probe

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