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TitlePotential 14-3-3 binding sites in sirtuins reveal extended phosphosite-recognition modes.
Journal, issue, pagesActa Crystallogr. ,Sect. F, Vol. 82, Page 32-40, Year 2026
Publish dateAug 5, 2022 (structure data deposition date)
AuthorsWeyand, M. / Quast, L. / Steegborn, C.
External linksActa Crystallogr. ,Sect. F / PubMed:41410196
MethodsX-ray diffraction
Resolution1.11 - 1.64 Å
Structure data

PDB-8anb:
14-3-3 sigma sirtuin-1 phospho-peptide complex
Method: X-RAY DIFFRACTION / Resolution: 1.64 Å

PDB-8anc:
14-3-3 sigma sirtuin-3 phospho-peptide complex
Method: X-RAY DIFFRACTION / Resolution: 1.11 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-CA:
Unknown entry

Source
  • homo sapiens (human)
KeywordsPEPTIDE BINDING PROTEIN / Human sirtuin / human 14-3-3 sigma / protein complex / phospho-peptide / NAD / deacetylase

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