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TitleStructural hijacking of FcRn by human astrovirus spikes reveals conserved epitopes for broad-spectrum antivirals.
Journal, issue, pagesCell Rep, Vol. 44, Page 116679-116679, Year 2025
Publish dateApr 23, 2025 (structure data deposition date)
AuthorsAgrawal, S. / Jain, M. / Marinelli, D. / Cho, S.Y. / Briney, B. / Wilson, I.A.
External linksCell Rep / PubMed:41389202
MethodsX-ray diffraction
Resolution2.97 - 3.07 Å
Structure data

PDB-9oc6:
Crystal structure of receptor FcRn bound to Human Astrovirus 6 spike
Method: X-RAY DIFFRACTION / Resolution: 2.97 Å

PDB-9oc7:
Crystal structure of FcRn in complex with Human Astrovirus 2 spike
Method: X-RAY DIFFRACTION / Resolution: 3.07 Å

Source
  • homo sapiens (human)
  • human astrovirus 6
  • human astrovirus 2
KeywordsIMMUNE SYSTEM / Astrovirus / FcRn / virus host interaction / HAstV

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