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TitleStructure, substrate recognition and therapeutic targeting of the human ADAMTS-5 spacer domain.
Journal, issue, pagesActa Crystallogr D Struct Biol, Vol. 82, Page 53-61, Year 2026
Publish dateJul 9, 2025 (structure data deposition date)
AuthorsMilani, M. / Visintin, M. / Krastanova, I. / Visentini, M. / Margotti, E. / Ugolini, G. / Bolognesi, M. / Rovati, L.C. / Mastrangelo, E.
External linksActa Crystallogr D Struct Biol / PubMed:41334750
MethodsX-ray diffraction
Resolution2.6 Å
Structure data

PDB-9rwm:
Crystal structure of human ADAMTS-5 Cb and Spacer domains
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsPROTEIN BINDING / spacer domain / jelly-roll / Cys rich domain

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