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TitleSynthesis of 2'-O,4'-C alpha-Dimethyl Ribonucleoside Analogs and Their Effects on RNA and Modulation of ADAR Editing.
Journal, issue, pagesChemistry, Vol. 32, Page e02958-e02958, Year 2026
Publish dateAug 12, 2025 (structure data deposition date)
AuthorsJauregui-Matos, V. / Brinkman, H.F. / Salvador, P.J. / Jacobs, O. / Cheng, J. / Mozumder, S. / Vu, T. / Fisher, A.J. / Beal, P.A.
External linksChemistry / PubMed:41318945
MethodsX-ray diffraction
Resolution1.801 - 2 Å
Structure data

PDB-9q0i:
Structure of dsRNA 16mer containing 4'-C-methyladenosine
Method: X-RAY DIFFRACTION / Resolution: 1.801 Å

PDB-9q0j:
Structure of dsRNA 16mer containing 4'-C-methyluridine
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-SPM:
SPERMINE

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsRNA / dsRNA / oligonucleotide / 4'-C-methyladenosine / 5-bromouridine / 4'-C-methyluridine

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