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TitleUnraveling the Prevalence and Multifaceted Roles of Accessory Peptide Deformylases in Bacterial Adaptation and Resistance.
Journal, issue, pagesMol. Biol. Evol., Vol. 42, Year 2025
Publish dateMar 12, 2025 (structure data deposition date)
AuthorsLamberioux, M. / Ducos-Galand, M. / Kaminski, P.A. / Littner, E. / Betton, J.M. / Mechaly, A. / Haouz, A. / Mazel, D.
External linksMol. Biol. Evol. / PubMed:41316864
MethodsX-ray diffraction
Resolution1.52 - 1.82 Å
Structure data

PDB-9qfr:
Crystal structure of Def1 in complex with actinonin
Method: X-RAY DIFFRACTION / Resolution: 1.52 Å

PDB-9qft:
Crystal structure of Def2 in complex with actinonin
Method: X-RAY DIFFRACTION / Resolution: 1.82 Å

Chemicals

ChemComp-NI:
NICKEL (II) ION

ChemComp-BB2:
ACTINONIN / antitumor, antibiotic*YM

ChemComp-HOH:
WATER

Source
  • vibrio cholerae o1 biovar el tor str. n16961 (bacteria)
KeywordsHYDROLASE / metalloprotease / antibiotic / protein translation

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