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Structure paper

TitleStructural and functional clues challenge the hypothesis that the yjdF riboswitch is natively regulated through broad recognition of azaaromatic compounds.
Journal, issue, pagesNucleic Acids Res., Vol. 53, Year 2025
Publish dateNov 12, 2024 (structure data deposition date)
AuthorsSpradlin, S.F. / Dickerson, K.A. / Batey, R.T.
External linksNucleic Acids Res. / PubMed:41277687
MethodsX-ray diffraction
Resolution2.519 - 2.853 Å
Structure data

PDB-9ebp:
Structure of the Bacillus subtilis yjdF riboswitch complexed with lumichrome in the presence of iridium hexammine
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

PDB-9ebv:
Structure of the Bacillus subtilis yjdF riboswitch aptamer domain in complex with lumichrome
Method: X-RAY DIFFRACTION / Resolution: 2.519 Å

PDB-9ec4:
Structure of the Bacillus subtilis yjdF riboswitch aptamer domain in complex with chelerythrine
Method: X-RAY DIFFRACTION / Resolution: 2.853 Å

Chemicals

ChemComp-LUM:
LUMICHROME

ChemComp-IRI:
IRIDIUM HEXAMMINE ION

ChemComp-HOH:
WATER

ChemComp-MG:
Unknown entry

ChemComp-K:
Unknown entry

ChemComp-CTI:
1,2-dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridin-12-ium / inhibitor, alkaloid*YM

ChemComp-BA:
Unknown entry

Source
  • synthetic construct (others)
  • bacillus subtilis subsp. subtilis str. 168 (bacteria)
KeywordsRNA / riboswitch / aptamer / lumichrome / iridium hexammine / yjdF / azaaromatic / flavin / chelerythrine

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