Database of articles cited by EMDB/PDB/SASBDB data

Keywords
Structure methods	All X-ray diffraction NMR electron microscopy small angle scattering neutron diffraction fiber diffraction powder diffraction infrared spectroscopy EPR fluorescence transfer theoretical model Hybrid
Author
Journal
IF	>30 >20 >10 >5 all

Title	Structural Rationalization of IPMK Inhibitor Potency.
Journal, issue, pages	J. Med. Chem., Vol. 68, Page 24316-24325, Year 2025
Publish date	Dec 4, 2023 (structure data deposition date)
Authors	Wang, H. / Shears, S.B. / Blind, R.D.
External links	J. Med. Chem. / PubMed:41237254
Methods	X-ray diffraction
Resolution	1.7 - 2 Å
Structure data	PDB-8v6w: Crystal structure of the core catalytic domain of human inositol phosphate multikinase in complex with compound 1 Method: X-RAY DIFFRACTION / Resolution: 1.95 Å PDB-8v6x: Crystal structure of the core catalytic domain of human inositol phosphate multikinase in complex with compound 2 Method: X-RAY DIFFRACTION / Resolution: 1.75 Å PDB-8v6y: Crystal structure of the core catalytic domain of human inositol phosphate multikinase in complex with compound 3 Method: X-RAY DIFFRACTION / Resolution: 1.7 Å PDB-8v6z: Crystal structure of the core catalytic domain of human inositol phosphate multikinase in complex with compound 4 Method: X-RAY DIFFRACTION / Resolution: 1.85 Å PDB-8v70: Crystal structure of the core catalytic domain of human inositol phosphate multikinase in complex with compound 6 Method: X-RAY DIFFRACTION / Resolution: 1.85 Å PDB-8v71: Crystal structure of the core catalytic domain of human inositol phosphate multikinase in complex with compound 7 Method: X-RAY DIFFRACTION / Resolution: 1.7 Å PDB-8v72: Crystal structure of the core catalytic domain of human inositol phosphate multikinase in complex with compound 8 Method: X-RAY DIFFRACTION / Resolution: 2 Å PDB-8v73: Crystal structure of the core catalytic domain of human inositol phosphate multikinase in complex with compound 9 Method: X-RAY DIFFRACTION / Resolution: 1.9 Å PDB-8v74: Crystal structure of the core catalytic domain of human inositol phosphate multikinase in complex with compound 10 Method: X-RAY DIFFRACTION / Resolution: 1.85 Å PDB-8v75: Crystal structure of the core catalytic domain of human inositol phosphate multikinase in complex with compound 11 Method: X-RAY DIFFRACTION / Resolution: 1.85 Å PDB-8v76: Crystal structure of the core catalytic domain of human inositol phosphate multikinase in complex with compound 15 Method: X-RAY DIFFRACTION / Resolution: 1.9 Å PDB-8v77: Crystal structure of the core catalytic domain of human inositol phosphate multikinase in complex with compound 12 Method: X-RAY DIFFRACTION / Resolution: 1.95 Å PDB-8v78: Crystal structure of the core catalytic domain of human inositol phosphate multikinase in complex with compound 13 Method: X-RAY DIFFRACTION / Resolution: 1.96 Å PDB-8v79: Crystal structure of the core catalytic domain of human inositol phosphate multikinase in complex with compound 14 Method: X-RAY DIFFRACTION / Resolution: 1.95 Å
Chemicals	ChemComp, No image ChemComp-YHE: Unknown entry ChemComp-HOH: WATER ChemComp, No image ChemComp-YHH: Unknown entry ChemComp, No image ChemComp-YHN: Unknown entry ChemComp, No image ChemComp-YHS: Unknown entry ChemComp, No image ChemComp-YHW: Unknown entry ChemComp-SO4: SULFATE ION ChemComp, No image ChemComp-YI8: Unknown entry ChemComp, No image ChemComp-YIB: Unknown entry ChemComp, No image ChemComp-YIG: Unknown entry ChemComp, No image ChemComp-YJQ: Unknown entry ChemComp, No image ChemComp-YIK: Unknown entry ChemComp, No image ChemComp-YIU: Unknown entry ChemComp, No image ChemComp-YJ3: Unknown entry ChemComp, No image ChemComp-YJB: Unknown entry ChemComp, No image ChemComp-YJH: Unknown entry
Source	homo sapiens (human)
Keywords	TRANSFERASE/TRANSFERASE INHIBITOR / Structure-based inhibitor development / kinase / inhibitor / inositol polyphosphate / TRANSFERASE / TRANSFERASE-TRANSFERASE INHIBITOR complex / inositol polyphosphate kinase