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TitleAn engineered yeast cytosine deaminase with improved catalytic activity and stability for macrophage-mediated enzyme/prodrug therapy.
Journal, issue, pagesCommun Biol, Vol. 8, Page 1562-1562, Year 2025
Publish dateOct 16, 2024 (structure data deposition date)
AuthorsZheng, J. / Zhou, J. / Yung, K.W.Y. / Hu, Q. / Lee, M.M. / Chan, M.K.
External linksCommun Biol / PubMed:41233498
MethodsX-ray diffraction
Resolution1.439 Å
Structure data

PDB-9k1k:
Yeast Cytosine Deaminase mutant-M100H
Method: X-RAY DIFFRACTION / Resolution: 1.439 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

Source
  • saccharomyces cerevisiae (strain atcc 204508 / s288c) (yeast)
KeywordsANTITUMOR PROTEIN / Cytosine deaminase

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