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TitleStructural and biochemical characterization of a thermostable Bacillus subtilis L-asparaginase with antiproliferative effects on hematological cancer cell lines.
Journal, issue, pagesInt. J. Biol. Macromol., Vol. 333, Page 148804-148804, Year 2025
Publish dateApr 3, 2024 (structure data deposition date)
AuthorsBrandao, L.C. / da Silva Gomes, J.G. / Pinheiro, D.P. / Caetano, L.F. / Bezerra, M.R.L. / Pontes, L.Q. / Pinheiro, M.P. / de Aquino, A.V.F.G. / Silva, J.M.F. / Souza, P.F.N. ...Brandao, L.C. / da Silva Gomes, J.G. / Pinheiro, D.P. / Caetano, L.F. / Bezerra, M.R.L. / Pontes, L.Q. / Pinheiro, M.P. / de Aquino, A.V.F.G. / Silva, J.M.F. / Souza, P.F.N. / Furtado, C.L.M. / Pessoa, C. / Lourenzoni, M.R. / da Rocha, B.A.M. / Furtado, G.P.
External linksInt. J. Biol. Macromol. / PubMed:41203148
MethodsX-ray diffraction
Resolution1.3 Å
Structure data

PDB-9bad:
Crystal structure of Bacillus subtilis 168 L-asparaginase II with antileukemic activity
Method: X-RAY DIFFRACTION / Resolution: 1.3 Å

Chemicals

ChemComp-NA:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • bacillus subtilis subsp. subtilis str. 168 (bacteria)
KeywordsANTITUMOR PROTEIN / Enzyme / Leukemia / Recombinant

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