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TitleUnveiling FERONIA receptor kinase-mediated cellular mechanisms with a small-molecule inhibitor.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 122, Page e2515322122-e2515322122, Year 2025
Publish dateApr 3, 2025 (structure data deposition date)
AuthorsSun, M. / Lu, B. / Yang, Y. / Fan, J. / Ren, W. / Chu, X. / Gao, Y. / Wu, J. / Wang, J. / Ke, H. ...Sun, M. / Lu, B. / Yang, Y. / Fan, J. / Ren, W. / Chu, X. / Gao, Y. / Wu, J. / Wang, J. / Ke, H. / Liu, Z. / Dai, S. / Lei, X. / Li, C.
External linksProc. Natl. Acad. Sci. USA / PubMed:41196348
MethodsX-ray diffraction
Resolution1.9 Å
Structure data

PDB-9ubi:
Crystal structure of FERONIA kinase and Ferovicin inhibitor
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-OT5:
1-[6-(3,5-dichloro-4-hydroxyphenyl)-4-({trans-4-[(dimethylamino)methyl]cyclohexyl}amino)-1,5-naphthyridin-3-yl]ethanone

ChemComp-HOH:
WATER

Source
  • arabidopsis thaliana (thale cress)
KeywordsPLANT PROTEIN / natural product biosynthetic enzyme

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