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TitlePhosphorylation as a candidate regulatory mechanism for effector recruitment to tankyrase.
Journal, issue, pagesR Soc Open Sci., Vol. 12, Page 250824-250824, Year 2025
Publish dateMar 19, 2025 (structure data deposition date)
AuthorsBroadway, B.J. / Pollock, K. / Cronin, N. / Rottapel, R. / Sicheri, F. / Guettler, S.
External linksR Soc Open Sci. / PubMed:41103766
MethodsX-ray diffraction
Resolution2.31 Å
Structure data

PDB-9qjz:
Crystal structure of ARC4 from human Tankyrase 2 in complex with phosphorylated peptide from human MDC1
Method: X-RAY DIFFRACTION / Resolution: 2.31 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN / ANKYRIN REPEAT / PROTEIN-PROTEIN INTERACTION / SUBSTRATE RECRUITMENT / POLY(ADP-RIBOSYL)ATION / SIGNALING PROTEIN-PEPTIDE COMPLEX

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