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TitleSA-XV, a 15-amino acid fragment of host defense peptide S100A12, targets mitochondria and is protective against fungal infections.
Journal, issue, pagesJ. Biol. Chem., Vol. 301, Page 110743-110743, Year 2025
Publish dateMar 24, 2025 (structure data deposition date)
AuthorsAgarwal, R. / Biswas, K. / Agrawal, A. / Shankar, N.N. / Kundu, S. / Roy, D. / Son, D. / Harikishore, A. / Yennamalli, R.M. / Lee, D. ...Agarwal, R. / Biswas, K. / Agrawal, A. / Shankar, N.N. / Kundu, S. / Roy, D. / Son, D. / Harikishore, A. / Yennamalli, R.M. / Lee, D. / Bhunia, A. / Roy, S.
External linksJ. Biol. Chem. / PubMed:40975173
MethodsNMR (solution)
Structure data

PDB-9u7m:
Solution NMR structure of SA-XV peptide bound to SDS micelle.
Method: SOLUTION NMR

Source
  • homo sapiens (human)
KeywordsANTIMICROBIAL PROTEIN / STRUCTURE FROM CYANA 2.1 Antifungal peptide Microbial Keratitis Random Coil Loosely bound to SDS micelle

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