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Structure paper

TitleStructural mechanism of RECQ1 helicase in unfolding G-quadruplexes compared with duplex DNA.
Journal, issue, pagesNucleic Acids Res., Vol. 53, Year 2025
Publish dateJan 15, 2025 (structure data deposition date)
AuthorsSong, Z.Y. / Zhang, X. / Ai, X. / Huang, L.Y. / Hou, X.M. / Fosse, P. / Liu, N.N. / Mauffret, O. / Rety, S. / Xi, X.G.
External linksNucleic Acids Res. / PubMed:40966504
MethodsX-ray diffraction
Resolution2.42 - 3.69 Å
Structure data

PDB-9i0s:
Structure of RecQL-ADP complex from Bos taurus
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-9i16:
Structure of RecQL-dsDNA-ADP-AlF4 complex from Bos taurus
Method: X-RAY DIFFRACTION / Resolution: 2.82 Å

PDB-9i1p:
Structure of RecQL- Myc G-quadruplex - ADP complex from Bos taurus
Method: X-RAY DIFFRACTION / Resolution: 3.2 Å

PDB-9i22:
Structure of Human helicase RecQ1- Myc G-quadruplex - ADP complex
Method: X-RAY DIFFRACTION / Resolution: 2.42 Å

PDB-9i23:
Structure of Human helicase RecQ1- 795-2T G-quadruplex - ADP complex
Method: X-RAY DIFFRACTION / Resolution: 3.69 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-ADP:
ADENOSINE-5'-DIPHOSPHATE / ADP, energy-carrying molecule*YM

ChemComp-MG:
Unknown entry

ChemComp-PO4:
PHOSPHATE ION

ChemComp-HOH:
WATER

ChemComp-K:
Unknown entry

ChemComp-PGE:
TRIETHYLENE GLYCOL

Source
  • bos taurus (domestic cattle)
  • homo sapiens (human)
KeywordsHYDROLASE / helicase DNA G-quadruplex

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