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TitleA choanoflagellate cGLR-STING pathway reveals evolutionary links between bacterial and animal immunity.
Journal, issue, pagesBiorxiv, Year 2025
Publish dateAug 13, 2025 (structure data deposition date)
AuthorsLi, Y. / Toyoda, H.C. / Fernandez, S.G. / Tiwari, B. / McNairy, C. / Woznica, A. / Kranzusch, P.J.
External linksBiorxiv / PubMed:40950183
MethodsX-ray diffraction
Resolution2.65 Å
Structure data

PDB-9q1f:
Choanoflagellate Salpingoeca macrocollata STING
Method: X-RAY DIFFRACTION / Resolution: 2.65 Å

Chemicals

ChemComp-1SY:
cGAMP

ChemComp-HOH:
WATER

Source
  • salpingoeca macrocollata (eukaryote)
KeywordsIMMUNE SYSTEM / Innate immunity / Cyclic dinucleotide signaling / Stimulator of Interferon Genes / cGAS-STING

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