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-Structure paper
| Title | De Novo Design of Miniprotein Inhibitors of Bacterial Adhesins. |
|---|---|
| Journal, issue, pages | Biorxiv, Year 2025 |
| Publish date | Aug 13, 2025 (structure data deposition date) |
 Authors | Chazin-Gray, A.M. / Thompson, T.R. / Lopatto, E.D.B. / Magala, P. / Erickson, P.W. / Hunt, A.C. / Manchenko, A. / Aprikian, P. / Tchesnokova, V. / Basova, I. ...Chazin-Gray, A.M. / Thompson, T.R. / Lopatto, E.D.B. / Magala, P. / Erickson, P.W. / Hunt, A.C. / Manchenko, A. / Aprikian, P. / Tchesnokova, V. / Basova, I. / Sanick, D.A. / Tamadonfar, K.O. / Timm, M.R. / Pinkner, J.S. / Dodson, K.W. / Kang, A. / Joyce, E. / Bera, A.K. / Schmitz, A.J. / Ellebedy, A.H. / Hvorecny, K.L. / Cartwright, M.J. / Vernet, A. / Bardales, S. / White, D. / Klevit, R.E. / Sokurenko, E.V. / Hultgren, S.J. / Baker, D. |
 External links | Biorxiv / PubMed:40894640 |
| Methods | X-ray diffraction |
| Resolution | 1.35 - 1.75 Å |
| Structure data |  PDB-9q1h:  PDB-9q1v: |
| Chemicals |  ChemComp-HOH: |
| Source |
|
 Keywords | PROTEIN BINDING / Inhibitor / Complex / de novo protein / adhesin / de novo design / multidrug-resistant / bacterial infections / Bacterial Adhesins / Miniprotein Inhibitors |
acinetobacter baumannii acicu (bacteria)
escherichia coli (E. coli)