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Structure paper

TitleStructural Basis of Novel Bile Acid-Based Modulators of FXR.
Journal, issue, pagesJ. Mol. Biol., Vol. 437, Page 169383-169383, Year 2025
Publish dateOct 23, 2024 (structure data deposition date)
AuthorsKydd-Sinclair, D. / Packer, G.L. / Weymouth-Wilson, A.C. / Watson, K.A.
External linksJ. Mol. Biol. / PubMed:40803552
MethodsX-ray diffraction
Resolution2.6 - 3.1 Å
Structure data

PDB-9h65:
Steroidal Selective Modulators of FXR with Therapeutic Potential
Method: X-RAY DIFFRACTION / Resolution: 3.1 Å

PDB-9h66:
Steroidal Selective Modulators of FXR with Therapeutic Potential
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals


ChemComp, No image

ChemComp-RJC:
Unknown entry

ChemComp-HOH:
WATER


ChemComp, No image

ChemComp-R3U:
Unknown entry

Source
  • homo sapiens (human)
KeywordsNUCLEAR PROTEIN / nuclear receptor / ligand binding domain / complex

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