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TitleGalectin-8 binding to alpha-1 antitrypsin is a physiological mechanism in healthy individuals but exacerbates the symptoms of alpha-1 antitrypsin deficiency.
Journal, issue, pagesArch. Biochem. Biophys., Vol. 772, Page 110577-110577, Year 2025
Publish dateNov 9, 2024 (structure data deposition date)
AuthorsSayed, H. / Mayo, K.H. / Zhou, Y. / Tai, G. / Su, J.
External linksArch. Biochem. Biophys. / PubMed:40780418
MethodsX-ray diffraction
Resolution1.75 Å
Structure data

PDB-9kh4:
Crystal structure of Galectin-8 N-CRD with N-acetyllactosamine
Method: X-RAY DIFFRACTION / Resolution: 1.75 Å

Chemicals

ChemComp-NA:
Unknown entry


ChemComp, No image

ChemComp-RNQ:
Unknown entry

ChemComp-NI:
NICKEL (II) ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsSUGAR BINDING PROTEIN / Crystal structure of Galectin-8 N-CRD with N-acetyllactosamine

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