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Structure paper

TitleCrystal structure-guided revelation of metal ion-dependent functional ambiguity in Pseudomonas aeruginosa histidinol dehydrogenase.
Journal, issue, pagesFebs J., Vol. 292, Page 6432-6453, Year 2025
Publish dateJan 9, 2024 (structure data deposition date)
AuthorsBasu Choudhury, G. / Chatterjee, R. / Saha, A. / Sarkar, D.J. / Das, B.K. / Datta, S.
External linksFebs J. / PubMed:40729526
MethodsX-ray diffraction
Resolution1.75 - 2.33 Å
Structure data

PDB-8xsq:
Pseudomonas aeruginosa Histidinol dehydrogenase native structure without Zn+
Method: X-RAY DIFFRACTION / Resolution: 1.75 Å

PDB-9ivy:
Pseudomonas aeruginosa Histidinol dehydrogenase with NADH and Zn
Method: X-RAY DIFFRACTION / Resolution: 2.33 Å

PDB-9lbv:
Pseudomonas aeruginosa Histidinol dehydrogenase with ADPP
Method: X-RAY DIFFRACTION / Resolution: 1.85 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-ACY:
ACETIC ACID

ChemComp-GOL:
GLYCEROL

ChemComp-ZN:
Unknown entry

ChemComp-NAI:
1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE

ChemComp-ADP:
ADENOSINE-5'-DIPHOSPHATE / ADP, energy-carrying molecule*YM

Source
  • pseudomonas aeruginosa (bacteria)
KeywordsOXIDOREDUCTASE / Dehydrogenase / Histidinol dehydrogenase

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